Cyclopeptide alkaloids
نویسندگان
چکیده
منابع مشابه
New 14-Membered Cyclopeptide Alkaloids from Zizyphus oxyphylla Edgew
Two new 14-membered cyclopeptide alkaloids, Oxyphylline B (4) and Oxyphylline C (5), along with three known 13-membered cyclopeptide alkaloids, were isolated from stem and roots of Zizyphus oxyphylla Edgew. The compounds were tested for antibacterial activity. Oxyphylline B (4) showed comparatively better antibacterial activities against Escherichia coli (MIC, 5 μg/mL) than other compounds. Thi...
متن کاملAntiplasmodial Activity, Cytotoxicity and Structure-Activity Relationship Study of Cyclopeptide Alkaloids.
Cyclopeptide alkaloids are polyamidic, macrocyclic compounds, containing a 13-, 14-, or 15-membered ring. The ring system consists of a hydroxystyrylamine moiety, an amino acid, and a β-hydroxy amino acid; attached to the ring is a side chain, comprised of one or two more amino acid moieties. In vitro antiplasmodial activity was shown before for several compounds belonging to this class, and in...
متن کامل- A Consideration of Requirements for Cyclopeptide Structures
Three lipocyclopeptides, aspartocins A (1), B (2), and C (3), were obtained from the aspartocin complex by reversed-phase HPLC separation. Their structures were elucidated by spectroscopic studies coupled with the previously published chemical degradation results. All three compounds, 1, 2, and 3, share the same cyclic decapeptide core of cyclo(Dab2-Pip3-MeAsp4-Asp5-Gly6-Asp7-Gly8-Dab9-Val10-Pr...
متن کاملAn Improved Branch and Bound Algorithm for Cyclopeptide Sequencing
15 Abstract— The mass-production of antibiotics and medication has started an evolutionary race between antibiotics and bacteria. Pharmaceutical companies proved helpful to create new antibiotics, while pathogens developed a new level of resistance to these antibiotics. Growth of drug-resistant disease increases the challenge of searching for new, more effective antibiotics. The isolation and s...
متن کاملPeptide alkaloids from Zizyphus sativa bark.
Two new cyclopeptide alkaloids, sativanine-N and sativanine-O were isolated from the stem bark of Zizyphussativa and their structures were established by spectral analysis.
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ژورنال
عنوان ژورنال: Phytochemistry Reviews
سال: 2016
ISSN: 1568-7767,1572-980X
DOI: 10.1007/s11101-016-9484-y